Yihua Zhang Selected Research

bifendate

1/2016	Anticancer efficacy of a nitric oxide-modified derivative of bifendate against multidrug-resistant cancer cells.
12/2014	Bifendate-chalcone hybrids: a new class of potential dual inhibitors of P-glycoprotein and breast cancer resistance protein.

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Yihua Zhang Research Topics

Disease

39	Neoplasms (Cancer) 04/2022 - 08/2008
11	Ischemic Stroke 01/2022 - 07/2011
11	Hepatocellular Carcinoma (Hepatoma) 11/2019 - 02/2010
6	Infections 01/2022 - 03/2015
6	Brain Ischemia (Cerebral Ischemia) 11/2020 - 12/2012
6	Thrombosis (Thrombus) 06/2017 - 07/2011
5	Inflammation (Inflammations) 03/2020 - 07/2010
5	Alzheimer Disease (Alzheimer's Disease) 04/2014 - 05/2012
4	Lung Neoplasms (Lung Cancer) 12/2019 - 07/2010
3	Breast Neoplasms (Breast Cancer) 04/2022 - 08/2014
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 11/2012
3	Ischemia 12/2021 - 01/2012
3	Hypoxia (Hypoxemia) 12/2021 - 01/2019
3	Neoplasm Metastasis (Metastasis) 01/2020 - 01/2018
3	Colorectal Neoplasms (Colorectal Cancer) 01/2020 - 12/2015
3	Melanoma (Melanoma, Malignant) 01/2020 - 05/2017
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2019 - 07/2010
3	Liver Neoplasms (Liver Cancer) 11/2019 - 08/2008
3	Carcinoma (Carcinomatosis) 01/2019 - 08/2008
3	Brain Infarction 01/2018 - 01/2012
3	Leukemia 01/2017 - 04/2009
2	Prostatic Neoplasms (Prostate Cancer) 04/2022 - 07/2003
2	Bites and Stings (Sting) 01/2022 - 11/2020
2	Bullous Pemphigoid (Pemphigoid) 11/2021 - 01/2021
2	Hyperglycemia 01/2021 - 05/2014
2	Disease Progression 01/2021 - 01/2021
2	Heart Failure 11/2020 - 11/2012
2	Virus Diseases (Viral Diseases) 11/2020 - 01/2020
2	Stroke (Strokes) 12/2019 - 01/2012
2	Pulmonary Arterial Hypertension 01/2019 - 01/2018
2	Right Ventricular Hypertrophy 01/2019 - 01/2018
2	Acute Lung Injury 09/2015 - 03/2015
2	Mitochondrial Diseases (Mitochondrial Disease) 11/2014 - 01/2012
2	B-Cell Lymphoma (Lymphoma, B Cell) 07/2014 - 01/2014
2	Infarction (Infarctions) 12/2012 - 08/2012

Drug/Important Bio-Agent (IBA)

28	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2021 - 08/2008
15	Biological ProductsIBA 01/2022 - 08/2008
13	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2014
12	Pharmaceutical PreparationsIBA 01/2021 - 07/2010
11	3-n-butylphthalide (butylphthalide)IBA 01/2022 - 07/2011
9	Oleanolic AcidIBA 04/2022 - 08/2008
6	1,2,5-oxadiazole 2-oxideIBA 06/2013 - 08/2008
5	Nitric Oxide DonorsIBA 01/2020 - 03/2015
5	CytokinesIBA 01/2020 - 03/2015
5	EnzymesIBA 07/2018 - 07/2003
5	bardoxolone methylIBA 04/2018 - 03/2015
4	Glucose (Dextrose)FDA LinkGeneric 12/2021 - 01/2012
4	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2019 - 03/2016
4	Glutathione Transferase (Glutathione S-Transferase)IBA 11/2019 - 06/2013
4	diazeniumdiolateIBA 04/2018 - 05/2012
4	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 12/2014 - 04/2012
4	Sorafenib (BAY 43-9006)FDA Link 07/2014 - 05/2010
3	Antiviral Agents (Antivirals)IBA 01/2022 - 01/2020
3	Oxygen (Dioxygen)IBA 12/2021 - 01/2012
3	Therapeutic UsesIBA 01/2021 - 01/2017
3	Particulate MatterIBA 03/2020 - 10/2019
3	piperlongumineIBA 01/2020 - 09/2017
3	tetramethylpyrazineIBA 01/2020 - 03/2016
3	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 12/2019 - 05/2017
3	Caspase 3 (Caspase-3)IBA 12/2019 - 02/2015
3	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 10/2018 - 06/2016
3	CollagenIBA 01/2018 - 08/2011
3	Antineoplastic Agents (Antineoplastics)IBA 01/2018 - 03/2015
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 08/2014 - 08/2011
3	Tacrine (Cognex)FDA Link 12/2013 - 05/2013
3	Flurbiprofen (Froben)FDA LinkGeneric 12/2013 - 05/2013
3	farnesylthiosalicylic acidIBA 06/2011 - 05/2010
2	Tyrosine (L-Tyrosine)FDA Link 01/2022 - 01/2018
2	Interferon Type IIBA 01/2022 - 01/2020
2	Non-Receptor Type 6 Protein Tyrosine PhosphataseIBA 01/2022 - 01/2020
2	dupilumabIBA 11/2021 - 01/2021
2	Free RadicalsIBA 03/2021 - 08/2012
2	Acrolein (Aqualin)IBA 03/2021 - 09/2015
2	GlucocorticoidsIBA 01/2021 - 02/2007
2	beta-Arrestin 1IBA 11/2020 - 01/2020
2	Cisplatin (Platino)FDA LinkGeneric 11/2020 - 12/2019
2	Peptides (Polypeptides)IBA 10/2020 - 09/2015
2	ZincIBA 12/2019 - 06/2015
2	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 12/2019 - 01/2019
2	ProdrugsIBA 11/2019 - 06/2013
2	PolymersIBA 11/2019 - 10/2019
2	MonocrotalineIBA 01/2019 - 01/2018
2	AcidsIBA 04/2018 - 06/2006
2	bardoxoloneIBA 04/2018 - 03/2015
2	Neuroprotective AgentsIBA 01/2018 - 08/2012
2	salicylhydroxamic acid (SHAM)IBA 01/2018 - 11/2004
2	Isosorbide FDA Link 01/2018 - 04/2013
2	bifendateIBA 01/2016 - 12/2014
2	Histone Deacetylases (Histone Deacetylase)IBA 12/2015 - 06/2015
2	EdaravoneIBA 09/2015 - 08/2012
2	Epinephrine (Adrenaline)FDA LinkGeneric 08/2014 - 08/2011
2	Cytochromes c (Cytochrome c)IBA 07/2014 - 01/2014
2	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 04/2013 - 08/2012
2	Arachidonic Acid (Vitamin F)IBA 08/2012 - 07/2010
2	oridoninIBA 06/2012 - 06/2012
2	AntigensIBA 06/2011 - 07/2003

Therapy/Procedure

15	Therapeutics 12/2021 - 08/2008
4	Drug Therapy (Chemotherapy) 01/2017 - 07/2010
3	Oral Administration 01/2022 - 01/2012
3	Immunotherapy 11/2017 - 05/2017